The multi-tissue epigenetic clock is published
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Steve Horvath reports a predictor of chronological age built from DNA methylation at 353 CpG sites that works across most human tissues. For the first time ageing has a cheap, quantitative, tissue-general readout — and immediately the question of whether that readout is a measure of ageing or a correlate of it.
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Connections · 1
- Epigenetic clocksconcerns
Assembled narrative · 1
Assembled from 13 blocks · 1 evidence · 8 related
- Story
- Steve Horvath reports a predictor of chronological age built from DNA methylation at 353 CpG sites that works across most human tissues. For the first time ageing has a cheap, quantitative, tissue-general readout — and immediately the question of whether that readout is a measure of ageing or a correlate of it.
- Knowledge
- Epigenetic clocks
- The multi-tissue epigenetic clock is published
- Connections
- Epigenetic clocks
- CALERIE (Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy)
- The missing surrogate endpoint for ageing
- The multi-tissue epigenetic clock is published
- Caloric restriction is reported to slow a pace-of-ageing measure
- Evidence
- Supports the multi-tissue epigenetic age predictor and its construction from 353 CpG sites. V55 verification basis: not retrieved; the article number is given as recalled and must be confirmed.
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