AlphaFold Protein Structure Database — release records, 2024 database paper, and database FAQ

evidence

The database opened in July 2021 with the human proteome and model organisms, expanded on 28 July 2022 to more than 200 million predicted structures covering effectively the whole of UniProt, and is reported in a 2024 database paper as covering over 214 million sequences; the FAQ states that AlphaFold has not been validated for predicting the effects of destabilising point mutations and that its output is a single conformation rather than a sample of a conformational ensemble. V55 verification basis: no EMBL-EBI page was fetched; search results carried the July 2022 two-hundredfold expansion, the 214-million figure and the paper title with attribution to EMBL-EBI, and carried the mutation and single-conformation limitations with attribution to the AlphaFold DB FAQ. The reported size at the July 2021 launch differs between summaries (figures near 300,000 and near 350,000 both appear) and is therefore not asserted. The adoption figures — over three million researchers in more than 190 countries by late 2025, over a million of them in low- and middle-income countries, and an independently analysed rise of over 40% in users' submissions of novel experimental structures — reached this record through secondary reporting of DeepMind and EMBL-EBI communications and require confirmation.

A evidence is not a place. Drawing it on a map would assert something about the world that no stored fact supports.