The NIA Interventions Testing Program begins
The United States National Institute on Aging establishes a programme to test candidate lifespan-extending compounds in genetically heterogeneous mice at three independent sites under a common protocol. It exists because single-laboratory, single-strain mouse lifespan results had proved poorly reproducible, and its most valuable output has been its list of failures.
Historical — it happened, and the record is settled.
Subjects
- NIA Interventions Testing Program · research programme · United States · not located
- Model organism lifespan research · research programme · not located
Evidence
Partly verified — Core facts are sourced; some optional detail is deliberately absent.
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
Supports the late-life lifespan extension by rapamycin replicated across the Interventions Testing Program's three sites. V55 verification basis: not retrieved; the specific percentage extensions and the sex difference are unchecked and are therefore not quoted numerically in the objects citing this record.
Nature · 2009 · Partly verified
Harrison D.E. et al. for the NIA Interventions Testing Program, Nature, vol. 460, 2009
Recorded on NIA Interventions Testing Program
- A single-gene mutation doubles nematode lifespan
- The NIA Interventions Testing Program begins
- Rapamycin extends mouse lifespan when started in late life
Related
Related because they share a subject in the Atlas — never because the text looks similar.