Smallpox reaches Tenochtitlan
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A smallpox epidemic swept the Mexica capital in the last months of 1520, in the interval between the expulsion of Cortés's force from the city and the siege that took it the following August. Among the dead was the ruler Cuitláhuac. The Nahua testimony gathered a generation later for Book XII of the Florentine Codex describes the disease from within the city: sores covering the body, immobility so complete that the sick could not turn over, and death by starvation for those with no one left able to bring them food. The military conquest of 1521 was conducted against a population already broken by an epidemic that had arrived ahead of the army.
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- Tenochtitlanconcerns
- The post-contact population collapse of the Americasconcerns
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